(ESR) Erythrocyte Sedimentation Rate
Test Name: ESR
Sample Type: Sodium Citrate 1.8
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The Erythrocyte Sedimentation Rate (ESR) is a blood test that can help detect inflammation in the body. It measures the rate at which red blood cells (erythrocytes) settle at the bottom of a test tube over a specified period, usually one hour.
How ESR Works:
- Sample Collection: Blood is drawn from a vein, typically in the arm.
- Procedure: The blood sample is placed in a tall, thin tube. The red blood cells slowly settle and form a sediment at the bottom of the tube.
- Measurement: The rate at which the red blood cells fall (sediment) is measured in millimeters per hour (mm/hr). The higher the rate, the more likely there is inflammation in the body.
What ESR Indicates:
- Inflammation: Elevated ESR levels can indicate inflammation caused by various conditions, including infections, autoimmune diseases, and cancers.
- Chronic Diseases: It can help monitor the activity of chronic inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus, and temporal arteritis.
- Infections: High ESR can point to infections like tuberculosis or bacterial endocarditis.
- Anemia: Some forms of anemia can also cause elevated ESR levels.
Factors Affecting ESR:
- Age and Sex: Normal ESR values can vary depending on age and sex. Generally, older individuals and females may have slightly higher normal values.
- Pregnancy: ESR can be elevated during pregnancy.
- Medications: Certain medications can influence ESR results.
Interpreting ESR Results:
- **Normal Range:** The normal range can vary slightly among laboratories, but generally:
- Men: 0-15 mm/hr
- Women: 0-20 mm/hr
- Children: 0-10 mm/hr
- Elevated ESR: Higher than normal results may indicate inflammation, infection, or other medical conditions.
- Low ESR: While less common, lower ESR values can be seen in conditions such as polycythemia or leukocytosis.
Limitations:
- Non-Specific: ESR is a non-specific test and does not pinpoint the exact cause of inflammation.
- **Used in Conjunction:** It's often used alongside other tests to diagnose and monitor conditions.
The ESR test is a simple and useful tool for detecting and monitoring inflammation, helping healthcare providers diagnose various conditions and track the effectiveness of treatments.
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